Publications

ARIZONA PROTEOMICS CONSORTIUM PUBLICATIONS, ABSTRACTS AND PATENTS

PUBLICATIONS

Mehus AA, Reed RJ, Lee VS, Littau SR, Hu C, Lutz EA, Burgess JL (2015). Comparison of Acute Health Effects From Exposures to Diesel and Biodiesel Fuel Emissions. J Occup Environ Med 2015; 57(7):705-12.

Csősz É, Emri G, Kalló G, Tsaprailis G, Tőzsér J. Highly abundant defense proteins in human sweat as revealed by targeted proteomics and label-free quantification mass spectrometry. J Eur Acad Dermatol Venereol. 2015 Aug 25. doi: 10.1111/jdv.13221. PMID:26307449.

Chaw RC, Correa-Garhwal SM, Clarke TH, Ayoub NA, Hayashi CY. Proteomic Evidence for Components of Spider Silk Synthesis from Black Widow Silk Glands and Fibers. J Proteome Res. 2015 Aug 24. PMID:26302244.

Yuan CC, Ma W, Schemmel P, Cheng YS, Liu J, Tsaprailis G, Feldman S, Ayme Southgate A, Irving TC. Elastic proteins in the flight muscle of Manduca sexta. Arch Biochem Biophys. 2015; 568:16-27. PMID: 25602701.

Typpo, KV, Larmonier CB, Deschenes J, Redford D, Kiela PR, Ghishan FK. Clinical characteristics associated with postoperative intestinal epithelial barrier dysfunction in children with congenital heart disease. Pediatr Crit Care Med. 2015; 16(1):37–44. PMID: 25162512.

Tian H, Li CS, Zhao KW, Wang JC, Duarte ME, David CL, Phan K, Atti E, Brochmann EJ, Murray SS. A carboxy terminal BMP/TGF-β binding site in secreted phosphoprotein 24 kD independently affects BMP-2 activity. J Cell Biochem. 2015; 116(4):667-76. PMID: 25418420.

Purohit R, Fritz BG, The J, Issaian A, Weichsel A, David CL, Campbell E, Hausrath AC, Rassouli-Taylor L, Garcin ED, Gage MJ, Montfort WR. YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit. Biochemistry. 2014; 53(1):101-14. PMID: 24328155.

Kang HJ, Kendrick S, Hecht SM, Hurley LH. The transcriptional complex between the BCL2 i-motif and hnRNP LL is a molecular switch for control of gene expression that can be modulated by small molecules. J Am Chem Soc. 2014; 136 (11):4172-85. PMID: 24559432.

Raulfs MD, Breci L, Bernier M, Hamdy OM, Janiga A, Wysocki V, Poutsma JC. Investigations of the mechanism of the "proline effect" in tandem mass spectrometry experiments: the "pipecolic acid effect". J Am Soc Mass Spectrom. 2014; 10:1705-15. PMID: 25078156.

Zobel-Thropp PA, Thomas EZ, David CL, Breci LA, Binford GJ. Plectreurys tristis venome: A proteomic and transcriptomic analysis. J Venom Res. 2014; 5:33-47. PMID: 25400903.

Nelp MT, Astashkin AV, Breci LA, McCarty RM, Bandarian V. The alpha subunit of nitrile hydratase is sufficient for catalytic activity and post-translational modification. Biochemistry. 2014; 53(24):3990-4. PMID: 24914472.

Jiang Y, Kong Q, Roland KL, Curtiss R 3rd. Membrane vesicles of Clostridium perfringens type A strains induce innate and adaptive immunity. Int J Med Microbiol. 2014; 304(3-4):431-43. PMID: 24631214.

Sollome JJ, Thavathiru E, Camenisch TD, Vaillancourt RR. HER2/HER3 regulates extracellular acidification and cell migration through MTK1 (MEKK4). Cell Signal 2014. 26:70-82. PMID 24036211. PMC3869707

Yassine HN, Jackson AM, Borges CR, Billheimer D, Koh H, Smith D, Reaven P, Lau SS, Borchers CH. The application of multiple reaction monitoring and multi-analyte profiling to HDL proteins. Lipids Health Dis. 2014; 13:8. PMID: 24397693.

Quintero, J, Figueroa DC, Barcelo, R, Breci, L, Astiazaran-Garcia, H, Rascon, L, Velazquez C. Identification of an immunogenic protein of Giardia lamblia using monoclonal antibodies generated from infected mice. Memórias Do Instituto
Oswaldo Cruz. 2013; 108(5):616–622. PMID: 23903978.

Rounds L, Havens CM, Feinstein Y, Friedman M, and Ravishankar S. Concentration-dependent inhibition of Escherichia coli O157:H7 and heterocyclic amines in heated ground beef patties by apple and olive extracts, onion powder and clove bud oil. Meat Sci. 2013; 94 (4):461-467. PMID: 23624435.

Isoe J, Scaraffia PY. Urea synthesis and excretion in Aedes aegypti mosquitoes are regulated by a unique cross-talk mechanism. PLoS One. 2013; 8(6): e65393. PMID: 23755226.

Monks TJ, Lau SS. Reactive intermediates: molecular and MS-based approaches to assess the functional significance of chemical-protein adducts. Toxicol Pathol. 2013; 41(2):315-21. PMID: 23222993.

Woo HH, Baker T, Laszlo C, Chambers SK. Nucleolin mediates microRNA-directed CSF-1 mRNA deadenylation but increases translation of CSF-1 mRNA. Mol Cell Proteomics. 2013; 12(6):1661-77. PMID: 23471483.

Laskay UA, Breci L, Vilcins IM, Dietrich G, Barbour AG, Piesman J, Wysocki VH. Survival of host blood proteins in Ixodes scapularis (Acari: Ixodidae) ticks: a time course study. J Med Entomol. 2013; 50(6):1282-90. PMID: 24843933.

Yassine H, Borges CR, Schaab MR, Billheimer D, Stump C, Reaven P, Lau SS, Nelson R. Mass spectrometric immunoassay and MRM as targeted MS-based quantitative approaches in biomarker development: potential applications to cardiovascular disease and diabetes. Proteomics. Clinical applications. 2013; 7(7-8):528-40. PMID: 23696124.

Fritz BG, Roberts SA, Ahmed A, Breci L, Li W, Weichsel A, Brailey JL, Wysocki VH, Tama F, Montfort WR. Molecular model of a soluble guanylyl cyclase fragment determined by small-angle X-ray scattering and chemical cross-linking. Biochemistry. 2013; 52(9):1568-82. PMID: 23363317

Hidalgo CG, Chung CS, Saripalli C, Methawasin M, Hutchinson KR, Tsaprailis G, Labeit S, Mattiazzi A, Granzier HL. The multifunctional Ca(2+)/calmodulin-dependent protein kinase II delta (CaMKIIδ) phosphorylates cardiac titin's spring elements. J Mol Cell Cardiol. 2013; 54:90-7. PMID: 23220127.

Mitchell SF, Jain S, She M, Parker R. Global analysis of yeast mRNPs. Nat Struct Mol Biol. 2013; 20:127-33. PMID: 23222640.

Wysocka-Kapcinska M, Torocsik B, Turiak L, Tsaprailis G, David CL, Hunt AM, Vekey K, Adam-Vizi V, Kucharczyk R, Chinopoulos C. The suppressor of AAC2 lethality SAL1 modulates sensitivity of heterologously expressed artemia ADP/ATP carrier to bongkrekate in yeast. PloS One. 2013; 29:8(9):e74187. PMID: 24073201.

Chuang Y, Xu X, Kwiatkowska A, Tsapraillis G, Hwang H, Petritis K, Flynn D, Symons M. Regulation of synaptojanin 2 5'-phosphatase activity by Src. Cell Adhes Migr. 2012; 6(6):518-25. PMID: 23076136.

Flores RJ, Li Y, Yu A, Shen J, Rao PH, Lau SS, Vannucci M, Lau CC, Man TK. A systems biology approach reveals common metastatic pathways in osteosarcoma. BMC Systems Biology. 2012; 6:50. PMID: 22640921.

Rounds L, Havens CM, Feinstein Y, Friedman M, and Ravishankar S. Plant extracts, spices, and essential oils inactivate Escherichia coli O157:H7 and reduce formation of potentially carcinogenic heterocyclic amines in cooked beef atties. J Agric Food Chem. 2012; 60 (14), 3792-9. PMID: 22397498.

Zhang J, Dinh TN, Kappeler K, Tsaprailis G, Chen QM. La autoantigen mediates oxidant induced de novo Nrf2 protein translation. Mol Cell Proteomics. 2012; 11(6):M111.015032. PMID: 22207702.

Bush DR, Wysocki VH, Scaraffia PY. Study of the fragmentation of arginine isobutyl ester applied to arginine quantification in Aedes aegypti mosquito excreta. J Mass Spectrom. 2012; 47(10): 1364–1371. PMID: 23019169.

Qin Y, Wysocki RJ Jr, Somogyi A, Feinstein Y, Franco YJ, Tsukamoto T, Dunatunga D, Levy C, Smith S, Simpson R, Gang D, Johnson MA, Palanivelu R. Sulfinylated azadecalins act as functional mimics of a pollen germination stimulant in Arabidopsis pistils. Plant J. 2011; 68(5): 800–815. PMID: 21801250.

Brown RV, Danford FL, Gokhale V, Hurley LH, Brooks TA. Demonstration that drug-targeted down-regulation of MYC in non-Hodgkins lymphoma is directly mediated through the promoter G-quadruplex. J Biol Chem. 2011; 286(47):41018-27. PMID: 21956115.

Wickramasekara S, Neilson J, Pate Nl, Breci L, Hilderbrand A, Maier RM, Wysocki V. Proteomics analyses of the opportunistic pathogen Burkholderia vietnamiensis using protein fractionations and mass spectrometry. J Biomed Biotechnol. 2011; 701928. PMID: 22187530.

Crabbé A, Schurr MJ, Monsieurs P, Morici L, Schurr J, Wilson JW, Ott CM, Tsaprailis G, Pierson DL, Stefanyshyn-Piper H, Nickerson CA. Transcriptional and proteomic responses of Pseudomonas aeruginosa PAO1 to spaceflight conditions involve Hfq regulation and reveal a role for oxygen. Appl Environ Microbiol. 2011; 77(4):1221-30. PMID: 21169425.

Cabello CM, Lamore SD, Bair WB 3rd, Davis AL, Azimian SM, Wondrak GT. DCPIP (2,6-dichlorophenolindophenol) as a genotype-directed redox chemotherapeutic targeting NQO1*2 breast carcinoma. Free Radical Res. 2011; 45(3):276-92. PMID: 21034357.

Kimzey MJ, Yassine HN, Riepel BM, Tsaprailis G, Monks TJ, Lau SS. New site(s) of methylglyoxal-modified human serum albumin, identified by multiple reaction monitoring, alter warfarin binding and prostaglandin metabolism. Chem –Biol Interact. 2011; 192(1-2):122-8. PMID: 20934417.

Ackermann MA, Kontrogianni-Konstantopoulos A. Myosin binding protein-c slow is a novel substrate for protein kinase A (PKA) and C (PKC) in skeletal muscle. J Proteome Res. 2011; 10(10): 4547–4555. PMID: 21888435.

Labenski MT, Fisher AA, Monks TJ, Lau SS. Mass spectrometry-based methods to identify chemical modifications on proteins. IV. Identification of chemical-adducted proteins in urine by multi-dimensional protein identification technology (LC/LC-MS/MS). In: Gautier, J.-C. (ed) Drug Safety Evaluation Series - Methods of Molecular Medicine. Humana Press 2011; Methods Mol Biol, 691:339-350.

Labenski MT, Fisher AA, Monks TJ, Lau SS. Mass spectrometry-based methods to identify chemical modifications on proteins. III. One-dimensional western blotting coupled to LC-MS/MS analysis to identify chemical-adducted proteins in rat urine. In: Gautier, J.-C. (ed) Drug Safety Evaluation Series - Methods of Molecular Medicine. Humana Press 2011; Methods Mol Biol 691:327-338.

Fisher AA, Labenski MT, Monks TJ, Lau SS. Mass spectrometry-based methods to identify chemical modifications on proteins: II. Utilization of LC-MS/MS analyses to identify site-specific chemical protein adducts in vitro. In: Gautier, J.-C. (ed.) Drug Safety Evaluation Series - Methods in Molecular Medicine. Humana Press 2011; Methods Mol Biol 691:317-326.

Fisher AA, Labenski MT, Monks TJ, Lau SS. Mass spectrometry-based methods to identify chemical modifications on proteins. I. Utilization of MALDI-TOF to determine chemical-protein adduct formation in vitro. In: Gautier, J.-C. (ed) Drug Safety Evaluation Series - Methods of Molecular Medicine. Humana Press 2011; Methods Mol Biol 691:303-316.

Yoon J-H, Choi E-J, Parker R. Dcp2 phosphorylation by Ste20 modulates stress granule assembly and mRNA decay in Saccharomyces cerevisiae. J Cell Biol. 2010; 189(5): 813–827. PMID: 20513766.

Jiang W, Wysocki VH, Dodds ED, Miesfeld RL, Scaraffia PY. Differentiation and quantification of C1 and C2 (13)C-labeled glucose by tandem mass spectrometry. Anal Biochem. 2010; 404(1):40-4. PMID: 20447372.

Xie L, Terrand J, Xu B, Tsaprailis G, Boyer J, Chen QM. Cystatin C increases in cardiac injury: a role in extracellular matrix protein modulation. Cardiovasc Res. 2010; 87(4):628-35. PMID: 20489058.

Daskalova SM, Radder JE, Cichacz ZA, Olsen SH, Tsaprailis G, Mason H, Lopez LC. Engineering of N. benthamiana L. plants for production of N-acetylgalactosamine-glycosylated proteins--towards development of a plant-based platform for production of protein therapeutics with mucin type O-glycosylation. BMC Biotechnol. 2010; 10:62. PMID: 20735851.

Labenski MT, Fisher AA, Lo H-H, Monks TJ, Lau SS. Protein electrophile-binding motifs: lysine-rich proteins are preferential targets of quinones. Drug Metab Dispos. 2009; 37(6): 1211–1218. PMID: 19251821.

Hruby VJ, Cai M, Dedek M, Qu H, Palmer E, Mayorov A, Trivedi D, Tsaprailis G, Yang Y. Peptide and non-peptide mimetics utilize different pathways for signal transduction. Adv Exp Med Biol. 2009; 611:305-307. PMID: 19400204.

Hidalgo C, Hudson B, Bogomolovas J, Zhu Y, Anderson B, Greaser M, Labeit S, Granzier H. PKC phosphorylation of titin's PEVK element. A novel and conserved pathway for modulating myocardial stiffness. Circ Res. 2009; 105(7): 631–638. PMID: 19679839.

Friedman M, Zhu L, Feinstein Y, Ravishankar S. Carvacrol facilitates heat-induced Inactivation of Escherichia coli O157:H7 and inhibits formation of heterocyclic amines in grilled ground beef patties. J Agric Food Chem. 2009; 57 (5), 1848-1853. PMID: 19222201.

Xie L, Pandey R, Xu B, Tsaprailis G, Chen QM. Genomic and proteomic profiling of oxidative stress response in human diploid fibroblasts. Biogerontol. 2009; 10(2):125-51. PMID: 18654835.

Leinweber BD, Tsaprailis G, Monks TJ, Lau SS. Improved MALDI-TOF imaging yields increased protein signals at high molecular mass. J Am Soc Mass Spectr. 2009; 20(1):89-95. PMID: 18926723.

Hruby VJ, Cai M, Dedek M, Qu H, Palmer E, Mayorov A, Trivedi D, Tsaprailis G, Yang Y. Peptide and non-peptide mimetics utilize different pathways for signal transduction. Adv Exp Med Biol. 2009; 611:305-7. PMID: 19400204.

Uemura T, Yerushalmi HF, Tsaprailis G, Stringer DE, Pastorian KE, Hawel L 3rd, Byus CV, Gerner EW. Identification and characterization of a diamine exporter in colon epithelial cells. J Biol Chem. 2008; 283(39):26428-35. PMID: 18660501.

Demetriou MC, Stylianou P, Andreou M, Yiannikouri O, Tsaprailis G, Cress AE, Skourides P. Spatially and temporally regulated alpha6 integrin cleavage during Xenopus laevis development. Biochem Biophys Res Commun. 2008; 366(3):779-85. PMID: 18083114.

Zhang J, Tsaprailis G, Bowden GT. Nucleolin stabilizes Bcl-X L messenger RNA in response to UVA irradiation. Cancer Res. 2008; 68(4):1046-54. PMID: 18281479.

Wilson JW, Ott CM, Quick L, Davis R, Höner zu Bentrup K, Crabbé A, Richter E, Sarker S, Barrila J, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Shah M, Nelman-Gonzalez M, Hing S, Parra M, Dumars P, Norwood K, Bober R, Devich J, Ruggles A, CdeBaca A, Narayan S, Benjamin J, Goulart C, Rupert M, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Porter MD, Pierson DL, Smith SM, Mergeay M, Leys N, Stefanyshyn-Piper HM, Gorie D, Nickerson CA. Media ion composition controls regulatory and virulence response of Salmonella in spaceflight. PloS One. 2008; 3(12):e3923. PMID: 19079590.

Scaraffia PY, Tan G, Isoe J, Wysocki VH, Wells MA, Miesfield RL. Discovery of alternate metabolic pathway for urea sysnthesis in adult Aedes aegypti mosquitoes. Proc Natl Acad Sci USA. 2008; 105(2): 518-523. PMID: 18182492.
Pizarro N, de la Torre R, Joglar J, Okumura N, Perfetti X, Lau SS, Monks TJ. Serotonergic neurotoxic thioether metabolites of 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy"): synthesis, isolation, and characterization of diastereoisomers. Chem Res Toxicol. 2008; 21:2272-2279. PMID: 19548351.

Sipes IG, Knudsen GA, Kuester RK. The effects of dose and route on the toxicokinetics and disposition of 1-butyl-3-methylimidazolium chloride in male F-344 rats and female B6C3F1 mice. Drug Metab Dispos. 2008; 36(2):284-293. PMID: 17967929.

Wilson JW, Ott CM, Höner zu Bentrup K, Ramamurthy R, Quick L, Porwollik S, Cheng P, McClelland M, Tsaprailis G, Radabaugh T, Hunt A, Fernandez D, Richter E, Shah M, Kilcoyne M, Joshi L, Nelman-Gonzalez M, Hing S, Parra M,
Dumars P, Norwood K, Bober R, Devich J, Ruggles A, Goulart C, Rupert M, Stodieck L, Stafford P, Catella L, Schurr MJ, Buchanan K, Morici L, McCracken J, Allen P, Baker-Coleman C, Hammond T, Vogel J, Nelson R, Pierson DL, Stefanyshyn-Piper HM, Nickerson CA. Space flight alters bacterial gene expression and virulence and reveals a role for global regulator Hfq. PNAS. 2007; 104(41):16299-304. PMID: 17901201.

Lantz RC, Lynch BJ, Boitano S, Poplin GS, Littau S, Tsaprailis G, Burgess JL. Pulmonary biomarkers based on alterations in protein expression after exposure to arsenic. Environ Health Perspect. 2007; 115(4):586-91. PMID: 17450228.

Wozniak RJ, Klimecki WT, Lau SS, Feinstein Y, Futscher BW. 5-Aza-2’-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation. Oncogene. 2007; 26, 77-90. PMID: 16799634.

Wen F, VanEtten HD, Tsaprailis G, Hawes MC. Extracellular proteins in pea root tip and border cell exudates. Plant Physiol. 2007; 143(2):773-83. PMID: 17142479.

Breci L, Haynes PA.Two-dimensional nanoflow liquid chromatography-tandem mass spectrometry of proteins extracted from rice leaves and roots. Methods Mol Biol. 2007; 355:249-66. PMID: 17093316.

Weichsel A, Brailey JL, Montfort WR. Buried S-nitrosocysteine revealed in crystal structures of human thioredoxin. Biochemistry. 2007; 46:1219-1227. PMID: 17260951

Rohrbough JG, Galgiani JN, Wysocki VH. The application of proteomic techniques to fungal protein identification and quantitation. Ann NY Acad Sci. 2007; 1111:133-146. PMID: 17344531.

Hattrup E, Neilson KA, Breci L, Haynes PA. Proteomic analysis of shade-avoidance in tomato leaves. J Ag Food Chem. 2007; 55(21):8310-8318. PMID: 17874839.

Rohrbough JG, Breci L, Merchant N, Miller S, Haynes PA. Verification of single-peptide protein identifications by the application of complementary database search algorithms. J Biomol Tech. 2006; 17(5): 327–332. PMID: 17122065.

Haynes PA, Miller S, Radabaugh T, Galligan M, Breci L, Rohrbough J, Hickman F, Merchant N. The Wildcat Toolbox: A set of perl script utilities for use in peptide mass spectral database searching and proteomics experiments. J Biomol Tech. 2006; 17(2): 97–102. PMID: 16741236.

Falsey RR, Marron MT, Kamal GM, Shirahatti N, Mahadevan D, Gutanilaka AAL, Whitesell L. Actin microfilament aggregation induced by withaferin A is mediated by annexin II. Nat Chem Biol. 2006; 2(1): 33-38. PMID: 16408090.

Baker AF, Dragovitch T, Tate WR, Ramanathan R, Roe D, Hsu C-H, Kirkpatrick DL, Powis G. (2006) The antitumor thioredoxin-1 inhibitor PX-12 (1-methylpropyl 2-imidazoyl disulfide) decreases thioredoxin-1 and VEGF levels in patient plasma. J Lab Clin Med. 2006; 147(2):83-90. PMID: 16459166.

Zhilina ZV, Ziemba AJ, Nielsen PE, Ebbinhaus SW. PNA-nitrogen mustard conjugates are effective suppressors of HER-2/neu and biological tools for recognition of PNA/DNA interactions. Bioconj Chem. 2006; 17:214-222. PMID: 16417271.

Ignatenko NA, Yerushalmi HF, Watts GS, Futscher BW, Stringer DE, Marton LJ, Gerner EW. Pharmacogenomics of the polyamine analog 3.8.13.18-tetrahydrochloride, CGC-11093, in the colon adenocarcinoma cell line HCT116. Tech Cancer Res Treat. 2006; 5(6):553-564. PMID: 17121431.

Labenski MT, Fisher AA, Tsaprailis G, Monks TJ, Lau SS. Identifying site-specific chemical modifications of urinary excreted protein using a proteomics approach. FASEB J. 2006; 20(4): A66.

Frigeri LG, Radabaugh TR, Haynes PA, Hildebrand M. Identification of proteins from a cell wall fraction of the diatom Thalassiosira pseudonana – insights into silica structure formation. 2006; Mol Cell Proteomics 5(1):182-193. PMID: 16207702.

Xie L, Tsaprailis G, Chen QM. Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts. Mol Cell Proteomics. 2005; 4(9):1273-83. PMID: 15958393.

Zakharyan RA, Tsaprailis G, Chowdhury UK, Hernandez A, Aposhian HV. Interactions of sodium selenite, glutathione, arsenic species, and omega class human glutathione transferase. Chem Res Toxicol. 2005; 18(8):1287-95. PMID: 16097802.

Kirkpatrick DS, Weldon SF, Tsaprailis G, Liebler DC, Gandolfi AJ. Proteomic identification of ubiquitinated proteins from human cells expressing His-tagged ubiquitin. Proteomics. 2005; 5(8):2104-11. PMID: 15852347.

Bair EL, Chen M-L, McDaniel K, Sekigushci K, Cress AE, Nagle RB, Bowden GT. Membrane-type-1 matrix metalloprotease (MT1-MMP) cleaves laminin-10 and promotes prostate cancer cell migration. Neoplasia 2005; 7(4):380-389. PMID: 15967115.

Derbyshire ZE, Halfter UM, Heimark RL, Vaillancourt RR. Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4, and annexin II. Mol. Cell Biochem. 2005; 271(1-2): 77-90. PMID: 15881658.

Medina ML, Haynes PA, Breci L, Francisco WA. Analysis of secreted proteins from Aspergillus flavus. Proteomics 2005; 5(12):3153-3161. PMID: 162035112.

Breci L, Hattrup E, Letarte J, Johnson R, Haynes PA. Comprehensive proteomics in yeast using chromatographic fractionation, gas phase fractionation, protein gel electrophoresis, and isoelectric focusing. Proteomics 2005; 5(8): 2018-2028. PMID: 15852344.

Tsaprailis G, Nair H, Zhong W, Kuppannan K, Futrell JH, Wysocki VH. A mechanistic investigation of the enhanced cleavage at histidine in the gas-phase dissociation of protonated peptides. Anal Chem. 2004; 76(7):2083-94. PMID: 15053674.

Nyman D, Stratton MS, Kopplin MJ, Dalkin BL, Nagle RB, Gandolfi AJ. Selenium and selenomethionine levels in prostate cancer patients. Cancer Detect Prev. 2004; 28(1):8-16. PMID: 15041072.

Sachs NA, Vaillancourt RR. Cyclin dependent kinase 11P110 and casein kinase 2 (CK2) inhibit the interaction between tyrosine hydroxylase and 14-3-3. J Neurochem. 2004; 88:51-62. PMID: 14675149.

Bernstein H, Payne CM, Kunke K, Crowley-Weber CL, Waltmire CN, Dvorakova K, Holubec H, Bernstein C, Vaillancourt RR, Raynes DA, Guerriero V, Garewal H. A proteomic study of resistance to deoxycholate-induced apoptosis. Carcinogenesis 2004; 25:1-24.PMID: 14729586.

Mikolajczyk M, Nelson MA Regulation of stability of cyclin-dependent kinase CDK11p110 and a caspase-processed form, CDK11p46, by Hsp90. Biochem. J. 2004; 384:461-467. PMID: 15344906.

Basha E, Lee GJ, Breci L, Hausrath AC, Buan NR, Giese KC, Vierling E. The identity of proteins associated with a small heat shock protein during heat stress in vivo indicates that these chaperones protect a wide range of cellular functions. J Biol Chem. 2004; 279(9):7566-7575. PMID: 14662763.

Alderton AL, Faustman C, Liebler DC, Hill DW. Induction of redox instability of bovine myoglobin by adduction with 4-hydroxy-2-nonenal. Biochemistry 2003; 2:4398-4405. PMID: 12693935.

Jones JA, Kaphalia L, Moslen MT, Liebler DC. Proteomic characterization of metabolism, protein adducts and hepatobiliary injury in rats exposed to 1,1-dichloroethylene and diclofenac. Chem Res Toxicol. 2003; 16:1306-1317. PMID: 14565772.

Liebler DC. Analysis of protein modifications with LC-MS and the SALSA algorithm: new tools for toxicology. Exp Lung Res. 2003; 29(Suppl. 1):88-92.

Mason DE, Liebler DC. Quantitative analysis of modified proteins by LC-MS-MS of peptides labeled with phenyl isocyanate. J Proteome Res. 2003; 2:265-272. PMID: 12814266.

Sachs NA and Vaillancourt RR. Cyclin-Dependent 11(p110) Activity in the Absence of CK2. Biochim Biophys Acta 2003; 1624 (1-3): 98-108. PMID: 1462819.

Shi J, Feng Y, Goulet AC, Vaillancourt RR, Sachs NA, Hershey JW, Nelson MA.The p34cdc2-related cyclin-dependent kinase 11 interacts with the p47 subunit of eukaryotic initiation factor 3 during apoptosis. J Biol Chem. 2003; 278: 5062-5071. PMID: 12446680.

Udayakumar TS, Chen ML, Bair EL, von Bredow DC, Cress AE, Nagle RB, Bowden GT. Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 beta3 chain and induces cell migration. Cancer Res. 2003; 63:2292-2299. PMID: 12727852.

Kalaitzis JA, Izumikawa M, Xiang L, Hertweck C, Moore BS. Mutasynthesis of enterocin and wailupemycin analogues. J Am Chem Soc. 2003; 125:9290-9291. PMID: 12889947.

Adams DG, Sachs NA, Vaillancourt RR. Phosphorylation of the stress-activated protein kinase, MEKK3, at serine 166. Arch Biochem Biophys. 2002; 407:103-116. PMID: 12392720.

Anderson WB, Liebler DC, Board PG, Anders MW. Mass spectral characterization of dichloroacetic acid-modified human glutathione transferase zeta. Chem Res Toxicol. 2002; 15:1387-1397. PMID: 12437329.

Badghisi H, Liebler DC. Sequence mapping of epoxide adducts in human hemoglobin with LC-tandem MS and the SALSA algorithm. Chem Res Toxicol. 2002; 15:799-805. PMID: 12067247.

Lantum HBM, Liebler DC, Board PG, Anders MW. Alkylation and inactivation of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone. Chem Res Toxicol. 2002; 15:707-16. PMID: 12018993.

Liebler DC. Proteomic approaches to characterize protein modifications: new tools to study the effects of environmental exposures. Environ Health Perspect. 2002; 110 (Suppl. 1): 3-9. PMID: 11834459.

Liebler DC, Hansen BT, Davey SW, Tiscareno L, Mason DE. Peptide sequence motif analysis of tandem MS data with the SALSA algorithm. Anal Chem. 2002; 74: 203-210. PMID: 11795795.

Radabaugh TR, Sampayo-Reyes A, Zakharyan RA, Aposhian HV. Arsenate reductase II. Purine nucleoside phosphorylase in the presence of dihydrolipoic acid is a route for reduction of arsenate to arsenite in mammalian systems. Chem Res Toxicol. 2002; 15:692-698. PMID: 12018991.

Terentis AC, Thomas SR, Burr JA, Liebler DC, Stocker R. Vitamin E oxidation in human atherosclerotic lesions. Circ Res. 2002; 90:333-339. PMID: 11861423.

Arora A, Willhite C, Liebler DC. Interactions of b-carotene and cigarette smoke in human bronchial epithelial cells. Carcinogenesis 2001; 22:1173-1178. PMID: 11470745.

Hansen BT, Mason DE, Jones JA, Liebler DC. SALSA: an algorithm for detection of modified peptides by automated evaluation of their CID spectra in LC-tandem MS analyses. Anal Chem. 2001; 73:1676-1683. PMID: 11338579.

Krol ES, Escalante DD, Liebler DC. Mechanisms of dimer and trimer formation from UV-irradiated alpha-tocopherol. Lipids. 2001; 36:49-55. PMID: 11214729.

Lauridsen C, Leonard SW, Griffin DA, Liebler DC, McClure TD, Traber MG. Quantitative analysis by liquid chromatography-tandem mass spectrometry of deuterium-labeled and unlabeled vitamin E in biological samples. Anal Biochem. 2001; 289:89-95. PMID: 11161299.

Zakharyan RA, Sampayo-Reyes A, Healy SM, Tsaprailis G, Board PG, Liebler DC, Aposhian HV. Human monomethylarsonic acid (MMA (V)) reductase is a member of the glutathione-S-transferase superfamily. Chem Res Toxicol. 2001; 14(8):1051-7. PMID: 11511179.

Arora A, Valcic S, Cornejo S, Nair MG, Timmermann BN, Liebler DC. Reactions of genistein with alkylperoxyl radicals. Chem Res Toxicol. 2000; 13:638-645. PMID: 10898596.

Jones JA, Liebler DC. Tandem MS analysis of model peptide adducts from reactive metabolites of the hepatotoxin 1,1-dichloroethylene. Chem Res Toxicol. 2000; 13:1302-1312. PMID: 11123972.

Krol ES, Kramer-Stickland KA, Liebler DC. Photoprotective actions of topically applied vitamin E. Drug Metab Rev. 2000; 32:413-420. PMID: 11139138.

Liebler DC, Burr JA. Antioxidant reactions of alpha-tocopherolhydroquinone. Lipids 2000; 35:1045-1047. PMID: 11026627.

Liebler DC, Burr JA. Effects of UV light and tumor promoters on vitamin E status in mouse skin. Carcinogenesis 2000; 21:221-225. PMID: 10657961.

Mason DE, Liebler DC. Characterization of benzoquinone peptide adducts by electrospray mass spectrometry. Chem Res Toxicol. 2000; 13:976-982. PMID: 11080046.

Valcic S, Burr JA, Timmermann BN, Liebler DC. Antioxidant chemistry of green tea catechins. New oxidation products of (-)-epigallocatechin gallate and (-)-epigallocatechin from their reactions with peroxyl radicals. Chem Res Toxicol. 2000; 13:801-810. PMID: 10995252.

Baker DL, Krol ES, Jacobsen N, Liebler DC. Reactions of b-carotene with cigarette smoke oxidants. Identification of carotenoid oxidation products evaluation of the prooxidant/antioxidant effect. Chem Res Toxicol. 1999; 12:535-543. PMID: 10368317.

Faustman C, Liebler DC, Burr JA. Alpha-tocopherol oxidation in beef and in bovine muscle microsomes. J Agric Food Chem. 1999; 47:1396-1399. PMID: 10563987.

Faustman C, Liebler DC, McClure TD, Sun Q. Alpha,beta-unsaturated aldehydes accelerate oxymyoglobin oxidation. J Agric Food Chem. 1999; 47:3140-3144. PMID: 10552621.

Halladay JS, Sauer JM, Sipes IG. Metabolism and disposition of [(14)C]1-nitronaphthalene in male Sprague-Dawley rats. Drug Metab Dispos. 1999; 27:1456-1465. PMID: 10570027.

Kramer-Stickland KA, Krol ES, Liebler DC. UV-B-Induced photooxidation of vitamin E in mouse skin. Chem Res Toxicol. 1999; 12:187-191. PMID: 10027797.

McVean M, Liebler DC. Prevention of DNA photodamage by topically applied vitamin E compounds and sunscreens: roles of ultraviolet absorbance and cellular uptake. Molec Carcinog. 1999; 24:169-176. PMID: 10204801.

Valcic S, Muders A, Jacobsen NE, Liebler DC, Timmermann BN. Antioxidant chemistry of green tea catechins. Identification of products of the reaction of (-)-epigallocatechin gallate with peroxyl radicals. Chem Res Toxicol 1999; 12:382-386. PMID: 10207128.

Sandrock RW, VanEtten HD. Fungal sensitivity to and enzymatic degradation of the phytoanticipin alpha-tomatine. Phytopathology. 1998; 88(2):137-143. PMID: 18944982.

MEETING ABSTRACTS

Metformin decreases glyco-oxidation markers: a study utilizing multiple reaction monitoring. Kinsky O, Kimzey M, Alfred S, Anumol T, Yassine H, Stump C, Tsaprails G, Snyder S, Bilheimer D, Monks T, Lau SS. Proceedings of the 61st ASMS Conference on Mass Spectrometry and Allied Topics. 61st ASMS Conference on Mass Spectrometry and Allied Topics; 2013; Minneapolis, MN, USA.

SAL1 modulates sensitivity of heterologously expressed artemia ADP/ATP carrier to bongkrekate in yeast. Kucharczyk R, Wysocka-Kapcinska M, Torocsik B, Turiak L, Tsaprailis G, David CL, Hunt AA, Vekey K, Adam-Vizi V, Chinopoulos C. 26th International Conference on Yeast Genetics and Molecular Biology; 2013; Frankfurt Main, Germany.

Simultaneous inactivation of Escherichia coli O157:H7 and reduction of potentially carcinogenic heterocyclic amines in heated ground beef patties by plant compounds. Rounds L, Havens CM, Feinstein Y, Friedman M, and Ravishankar S. Food Safety Meeting; 2013.

Site-specific arginine dicarbonyl modifications of serum albumin are reduced in metformin-controlled T2DM patients. Kinsky OR, Kimzey MJ, Alfred SF, Yassine HN, Tsaprailis G, Stump C, Billheimer D, Monks TJ, Lau SS. FASEB JOURNAL V26. Experimental Biology Meeting; 2012; San Diego, CA, USA.

4-Hydroxy-2-nonenal-modified proteins in bone marrow of phenol/hydroquinone treated rats: implications for benzene-mediated hematotoxicity. Kuhlman CL, Petersen DR, Tsaprailis G, Monks TJ, Lau SS. FASEB JOURNAL V26. Experimental
Biology Meeting; 2012; San Diego, CA, USA.

Development of an internal standard for studies of human plasma by label free quantitative analysis. Radabaugh T, Xu H, Tsaprailis G, Lu Z, Liu J, Billheimer D, Vercelli D, Halonen M, Lau SS. Proceedings of the 59th ASMS Conference on Mass Spectrometry and Allied Topics. 59th ASMS Conference on Mass Spectrometry and Allied Topics; 2011; Denver, CO, USA.

New site(s) of methylglyoxal-modified human serum albumin, identified by multiple reaction monitoring, alter warfarin binding and prostaglandin metabolism. Kimzey MJ, Yassine HN. 8th International Conference on Biological Reactive Intermediates; 2010; Barcelona, Spain.

Quantitation of proteomic markers of glyco-oxidation using multiple reaction monitoring. Kimzey MJ, Yassine HN, Galligan MA, Stump C, Tsaprailis G, Lau SS. Proceedings of the 58th ASMS Conference on Mass Spectrometry and Allied Topics. 58th ASMS Conference on Mass Spectrometry and Allied Topics; 2010; Salt Lake City, UT, USA.

Quantitative analysis of oxidative modifications in HDL using MRM. Yassine HN, Kimzey M, Galligan MA, Stump CS, Tsaprailis G, Lau SS. Proceedings of the 58th ASMS Conference on Mass Spectrometry and Allied Topics. 58th ASMS Conference on Mass Spectrometry and Allied Topics; 2010; Salt Lake City, UT, USA.

Effect of glyco-oxidative modifications on plasma fibrinogen function in diabetes. Yassine HN, Kimzey M, Galligan MA, Stump CS, Tsaprailis G, Lau SS. Proceedings of the 58th ASMS Conference on Mass Spectrometry and Allied Topics. 58th ASMS Conference on Mass Spectrometry and Allied Topics; 2010; Salt Lake City, UT, USA.

Proteomic analysis of human plasma in search of potential biomarkers associated with protection from asthma. Galligan M, Breci LA, Radabaugh TR, Tsaprailis G, Billheimer D, Halonen M, Vercelli D, Lau SS. Proceedings of the 58th ASMS Conference on Mass Spectrometry and Allied Topics. 58th ASMS Conference on Mass Spectrometry and Allied Topics; 2010; Salt Lake City, UT, USA.

Identification of candidate plasma biomarkers for diabetic complications: in vivo methylglyoxal modified hotspots. Kimzey M, Galligan M, Yassine H, Stump C, Tsaprailis G, Lau SS. Proceedings of the 57th ASMS Conference on Mass Spectrometry and Allied Topics. 57th ASMS Conference on Mass Spectrometry and Allied Topics; 2009; Philadelphia, PA, USA.

MALDI imaging of prostate cancer tissue toward validation of biomarker identification. Hattan C, Leinweber B, Nagle R, Gard J, Pestano G, Miller P, Froehlich J, Shi G, Kruppa G, Tsaprailis G, Lau SS. Proceedings of the 57th ASMS Conference on Mass Spectrometry and Allied Topics. 57th ASMS Conference on Mass Spectrometry and Allied Topics; 2009; Philadelphia, PA, USA.

Plasma methylglyoxal and correlation with the severity of diabetic albuminuria. Yassine H, Kimzey M, Alvarea I, Stratton S, Stump C, Tsaprailis G, Galligan MA, Lau SS. Proceedings of the 57th ASMS Conference on Mass Spectrometry and Allied Topics. 57th ASMS Conference on Mass Spectrometry and Allied Topics; 2009; Philadelphia, PA, USA.

Efficient strategies for identification of proteins in MALDI tissue images. Leinweber B, Tsaprailis G, Breci LA, David CL, Feinstein Y, Lau SS. Proceedings of the 56th ASMS Conference on Mass Spectrometry and Allied Topics. 56th ASMS Conference on Mass Spectrometry and Allied Topics; 2008; Denver, CO, USA.

Proteomic analysis of rat and human plasma in search of potential biomarkers for type 2 diabetes. Galligan M, Kimzey M, Radabaugh TR, Link DC, Borges CR, Yassine H, Henriksen EJ, Nelson R, Stump CS, Lau SS. Proceedings of the 56th ASMS Conference on Mass Spectrometry and Allied Topics. 56th ASMS Conference on Mass Spectrometry and Allied Topics; 2008; Denver, CO, USA.

Biofluid proteomic analysis in high fat-fed, insulin-resistant rats before the onset of diabetes. Stump CS, Tsaprailis G, Henriksen EJ, Galligan MA, Kimzey MJ, Teachey MK, Link CC, Lau SS. 67th Annual Meeting of the American-Diabetes-Association; 2008; San Francisco, CA, USA.

Identification of methyglyoxal modified proteins in diabetic plasma using MudPIT. Kimzey M, Galligan M, Radabaugh TR, Borgess CR, Yassine H, Nelson R, Stump C, Tsaprailis G, Link DC, Henrikson EJ, Lau SS. Proceedings of the 56th ASMS Conference on Mass Spectrometry and Allied Topics. 56th ASMS Conference on Mass Spectrometry and Allied Topics; 2008; Denver, CO, USA.

Identification of quinol-thioether-adducted proteins excreted in the urine after iv administration of 2-(glutathion-S-yl)HQ in long-evans rats. Labenski MT, Fisher AA, Tsaprailis G, Monks TJ, Lau SS. Meeting of the Division of Chemical Toxicology of the American-Chemical-Society held at the 234th ACS National Meeting; 2007; Boston, MA, USA.
Maximizing protein recovery from DIGE-analyzed gels through efficient spot excision to improve mass spectrometric analyses. Tsaprailis G, Isaac I. 2nd International Conference of the Hellenic-Proteomics-Society; 2007; Creete, Greece.
Peptide and non-peptide mimetics utilize different pathways for signal transduction Hruby VJ, Cai M, Dedek M, Tsaprailis G. 20th American-Peptide-Society Symposium; 2007; Montreal, Quebec, Canada.

Rational drug design for GPCR: molecular mechanism of agonist mediated cell signaling for melanocortin receptors. Dedek M, Yang Y, Palmer E, Tsaprailis G, Mayorov A, Trivedi D, Hruby V. 20th American-Peptide-Society Symposium; 2007; Montreal, Quebec, Canada.

Cai M, Tsaprailis G, Bordelon S, Qu H, Trivedi D, Hruby VJ. Cell signaling of melanocortin receptor I by mass spectrometric analysis. Proceedings of the 29th European Peptide Symposium; 2007; Geneva, Switzerland.

Arsenic: The king of poisons, the poisons of kings, and the bane of investigators. Aposhian VH, Avram MD, Tsaprailis G, Chowdhury UK. Meeting of the Division of Chemical Toxicology of the American-Chemical-Society held at the 232nd ACS National Meeting; 2006; San Francisco, CA, USA.

Identifying site-specific chemical modifications of urinary excreted proteins using a proteomics approach. Labenski MT, Fisher AA, Tsaprailis G, Monks TJ, Lau SS. Experimental Biology 2006 Meeting; 2006; San Francisco, CA, USA.

LC-MS approach of quantifying folates in tissues expressing N-Acetyl transferase. Shahab S, Erickson RP, Feinstein Y. University of Arizona Undergraduate Biology Research Program, Summer Poster Session; 2004; Tucson AZ, USA.

PATENT
Qin Y, Palanivelu R, Wysocki RJ JR, Somogyi A, Feinstein Y: Pollen tube stimulants from Arabidopsis pistils. The Arizona Board of Regents on behalf of the University of Arizona. Published on March 5, 2013: US8389728 B2